deoxyguanosine monophosphate
Học thuậtThân thiện
Definition
- Noun:
- A nucleotide constituent of DNA: Deoxyguanosine monophosphate is one of the four fundamental nucleotide monomers that form DNA molecules. It consists of the nucleoside deoxyguanosine linked to a single phosphate group.
Usage
- Scientific Context: This term is used almost exclusively in biochemistry, molecular biology, and genetics when discussing the structure, synthesis, or sequencing of DNA.
- The enzyme incorporates deoxyguanosine monophosphate into the growing DNA strand.
- A mutation occurred where a deoxyadenosine monophosphate was replaced by a deoxyguanosine monophosphate.
Advanced Usage
- Abbreviation (dGMP): In technical literature, it is commonly abbreviated as dGMP.
- The concentration of dGMP was measured in the sample.
- Role in the Genetic Code: As one of the four DNA building blocks, it pairs specifically with deoxycytidine monophosphate (dCMP) via hydrogen bonding in the DNA double helix.
Variants and Related Words
- Deoxyguanosine: The nucleoside component (deoxyribose sugar + guanine base) without the phosphate group.
- Guanosine monophosphate (GMP): The ribonucleotide equivalent found in RNA, containing ribose sugar instead of deoxyribose.
- Deoxyguanosine diphosphate (dGDP) and triphosphate (dGTP): Nucleotides with two and three phosphate groups, respectively; dGTP is the direct precursor used during DNA synthesis.
Synonyms
- dGMP: The standard biochemical abbreviation.
- Guanylic acid (deoxy form): An older, less specific chemical name.
Related Phrases/Concepts
- DNA nucleotide: Deoxyguanosine monophosphate is a specific type of DNA nucleotide.
- Nitrogenous base: It contains the purine base guanine.
- Complementary base pairing: It specifically base-pairs with deoxycytidine monophosphate.
Noun
- one of the four nucleotides used in building DNA; all four nucleotides have a common phosphate group and a sugar (ribose)